Imāmzādeh Hamzah (Persian: امامزاده سيد حمزه) is an Imamzadeh mosque-complex in Tabrīz, Iran. The mosque contains the grave of Hamzah, son of the Twelver Shī‘ah Imām, Mūsā' al-Kādhim.
The Imāmzādeh Hamzah mosque is located in the sheshghelan suburb of Tabrīz next to Maqbaratoshoara and the Museum of Ostad Bohtouni. It is also near Amir Nezam House, House of Seghat ol Islam and Saheb ol Amr Mosque. The mosque dates back to the 14th century (8th century A.H.), with influence from the Safavid and Qajar dynasties.